产品货号:
Z22521
中文名称:
p73/TP73抗体
英文名称:
Anti-p73/TP73 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-p73/TP73 Antibody |
指标别名 | tumor protein p73;P73;TP73 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | WB,IHC |
基因名称 | TP73 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | E.coli-derived human p73 recombinant protein (Position:M1-E198).Human p73 shares 96% amino acid (aa) sequence identity with mouse p73. |
实际分子量 | 73KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | p73,also known as tumor protein 73(TP73),encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development.It is mapped to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors,and thought to contain multiple tumor suppressor genes.The demonstration that this gene is monoallelically expressed (likely from the maternal allele),supports the notion that it is a candidate gene for neuroblastoma.Furthermore,recent finding are suggesting that over-expression of transcription factors involved in cell cycle regulation and synthesis of DNA in mammalian cells (e.g.:E2F-1) induces the expression of p73.In addition,p73 is a substrate of the c-Abl kinase and that the ability of c-Abl to phosphorylate p73 is markedly increased by gamma-irradiation. |
Uniprot ID | O15350 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
基因名全称 | tumor protein p73 |
蛋白名全称 | Tumor protein p73 |
推荐稀释比 | Western blot(WB) 1:500~2000 Immunohistochemistry in paraffin section (IHC) 1:50~400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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